Intraocular Pressure Course During the Femtosecond Laser-Assisted Cataract Surgery in Porcine Cadaver Eyes.

Purpose Femtosecond laser-assisted cataract surgery (FLACS) is an increasingly common procedure. Most laser systems require corneal applanation and thereby increase intraocular pressure (IOP). The purpose of the present study was to evaluate the IOP changes that occur during the FLACS procedure performed using the Catalys femtosecond laser system. Methods IOP was measured by direct cannulation of the vitreous body of porcine cadaver eyes (N = 20). By inserting a second cannula connected to a water column, all the eyes were set to a baseline IOP of 20 mm Hg. The eyes were lifted by custom-made stands to achieve the appropriate height and position under the Catalys system. The standard FLACS procedure was performed using varying fragmentation times to assess the influence of tissue fragmentation times on IOP peaks. Results We identified significant IOP elevations from baseline IOP levels during all steps of the FLACS procedure (baseline: 20.28 ± 1.32 mm Hg; vacuum: 34.48 ± 4.21 mm Hg; capture: 47.90 ± 13.02 mm Hg; lock: 48.41 ± 9.04 mm Hg; analysis: 47.15 ± 5.97 mm Hg; capsulotomy: 45.74 ± 6.52 mm Hg; fragmentation: 48.41 ± 6.80 mm Hg; end: 17.81 ± 1.61 mm Hg; all P < 0.001). Furthermore, the tissue fragmentation time had a significant effect on the peak IOP values detected (R = 0.62, P = 0.04, n = 9). Conclusions The present study reveals significant IOP increases during FLACS procedures carried out using the Catalys system.